{"id":280463,"date":"2024-09-20T11:12:17","date_gmt":"2024-09-20T09:12:17","guid":{"rendered":"https:\/\/uwr.edu.pl\/projektant-maszyn-molekularnych-rafal-grzelczak\/"},"modified":"2024-09-24T15:30:42","modified_gmt":"2024-09-24T13:30:42","slug":"molecular-machine-designer-rafal-grzelczak","status":"publish","type":"post","link":"https:\/\/uwr.edu.pl\/en\/molecular-machine-designer-rafal-grzelczak\/","title":{"rendered":"Molecular machine designer \u2013 Rafa\u0142 Grzelczak"},"content":{"rendered":"\n
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photo: Alina Metelytsia<\/figcaption><\/figure>\n<\/div>\n\n\n\n
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Molecular machine designer \u2013 Rafa\u0142 Grzelczak<\/h1>\n\n\n

The University of Wroc\u0142aw has high esteem for finalists and laureates of Olympiads, and candidates with excellent secondary school-leaving exam results, but most of all for those who wish to develop their interests and become \u201cYoung Researchers\u201d. Meet Rafa\u0142 Grzelczak.<\/p>\n<\/div>\n<\/div>\n\n\n\n

Scientists from the University of Warsaw, from the Polish Academy of Sciences, and from the Faculty of Chemistry of the University of Wroc\u0142aw<\/a>, including one of our young researchers Rafa\u0142 Grzelczak, have recently made great progress towards designing new molecular machines.<\/p>\n\n\n\n

Rafa\u0142 is in the research group of prof. Bartosz Szyszka at our University. It is this group that has recently obtained a new class of rotaxanes based upon calix[n]phyrins\u2014hybrids of porphyrinoids and calixpyrroles. The introduction of calix[n]phyrins into the rotaxane axle created a new type of molecular motion, so-called \u201cfluttering\u201d, not previously described in scholarly literature.  <\/p>\n\n\n\n

\u201cRafa\u0142 Grzelczak is a part of the Supramolecular Organic Chemistry Team. He managed to obtain an interesting group of rotaxanes while researching the synthesis of new molecules with chemical bonding for his dissertation\u201d, prof. Bartosz Szyszko emphasises.<\/p>\n\n\n\n

Recent research published by Grzelczak in the Angewandte Chemie <\/em>journal regards the implementation of a new type of motion\u2014\u201cfluttering\u201d\u2014into the molecular machines, possible through the application of a calix[n]phyrin ring into the molecule structure. \u201cAdditionally, we showcased an interesting approach in the synthesis of mechanically interlocked porphyrinoids and expanded the knowledge on the already existing types of motion in molecular machines. In my opinion, the paper is very rich and may create possibilities for many engaging projects\u201d, says Rafa\u0142 Grzelczak.<\/p>\n\n\n\n

Research details<\/strong><\/a><\/strong><\/p>\n\n\n\n

In his doctoral research, he is working on mechanically interlocked molecules. \u201cA mechanical bond is an entanglement of at least two chemical individuals in space, which form a unity despite not being linked through a covalent bond\u201d, Rafa\u0142 explains. \u201cThe simplest examples of objects with this property in the macroscopic world are chain links, a bracelet on one\u2019s hand, or an earring in one\u2019s ear. A physical nearing of such individuals enables the obtainment of tight spaces which imitate active sites of proteins. In addition, through the modifying of the entangled subunits, we are able to gain control over their motion towards each other. Such procedures turn a molecule into a molecular machine\u201d, he adds.<\/p>\n\n\n\n

The Young Researcher Grant helped Rafa\u0142 Grzelczak twice.<\/p>\n\n\n\n

First, during a conference in Cagliari. \u201cI stumbled upon the \u2018Young Researcher Grant\u2019 while searching for financial resources for this international conference. Since the programme was going to cover all trip-related expenses, I sent my application letter. A few weeks later I received information that I had been granted financial support.\u201d<\/p>\n\n\n\n

And again, during a conference in Paris. The grant was high enough to enable a calm and comfortable trip. \u201cParticipating in the conferences gave me a broader perspective on supramolecular chemistry, as I obtained the essence of the work of several research groups during several days of lectures and presentations\u201d, the young researcher says. \u201cThis makes it possible for me to search for new paths of application and development of my projects.\u201d<\/p>\n\n\n\n

\u201cEstablishing relations with PhD students working in teams I followed was crucial, it gave me the technical knowledge on how to properly perform chemical syntheses I found problematic. I also feel that participating in those conferences may help me choose the laboratory for my post-doctoral internship more advisedly. Besides, the trips had a cognitive and touristic asset\u201d, he says.<\/p>\n\n\n\n

Why did he choose the University of Wroc\u0142aw? \u201cA few people recommended it to me\u201d, he admits. \u201cDuring my university studies I attended prof. Bartosz Szyszko\u2019s laboratory classes on organic chemistry. I happened to be invited to join his team. The subject he proposed for my thesis sounded very exciting to me. After getting my master\u2019s degree, I decided it might be worth it to continue my research on a PhD programme.\u201d<\/p>\n\n\n\n

Plans? \u201cFirstly, a post-doctoral internship abroad. Further career plans will be getting clarified in the next year\u201d, he adds.<\/p>\n\n\n\n

More about the programme: Young Researcher, or scholarships for the best! – Uniwersytet Wroc\u0142awski (uwr.edu.pl)<\/a><\/p>\n\n\n\n

More about our young researchers: Scholarships and Young Researcher grants (IDUB) \u2013 University of Wroc\u0142aw (uwr.edu.pl)<\/a><\/p>\n\n\n\n

Edited by Katarzyna G\u00f3rowicz-Ma\u0107kiewicz<\/p>\n\n\n\n

Translated by Natalia Tkaczuk (student of English Studies at the University of Wroc\u0142aw) as part of the translation practice.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"

The University of Wroc\u0142aw has high esteem for finalists and laureates of Olympiads, and candidates with excellent secondary school-leaving exam results, but most of all for those who wish to develop their interests and become \u201cYoung Researchers\u201d. Meet Rafa\u0142 Grzelczak.<\/p>\n","protected":false},"author":630,"featured_media":279950,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[84,159],"tags":[],"class_list":["post-280463","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-ul-studies-and-students-en"],"featured_image_urls_v2":{"full":["https:\/\/uwr.edu.pl\/wp-content\/uploads\/2024\/09\/Rafal-Grzelczak_fot.Alina-Metelytsia_13-3-scaled.jpg",2560,1707,false],"thumbnail":["https:\/\/uwr.edu.pl\/wp-content\/uploads\/2024\/09\/Rafal-Grzelczak_fot.Alina-Metelytsia_13-3-150x150.jpg",150,150,true],"medium":["https:\/\/uwr.edu.pl\/wp-content\/uploads\/2024\/09\/Rafal-Grzelczak_fot.Alina-Metelytsia_13-3-300x200.jpg",300,200,true],"medium_large":["https:\/\/uwr.edu.pl\/wp-content\/uploads\/2024\/09\/Rafal-Grzelczak_fot.Alina-Metelytsia_13-3-768x512.jpg",768,512,true],"large":["https:\/\/uwr.edu.pl\/wp-content\/uploads\/2024\/09\/Rafal-Grzelczak_fot.Alina-Metelytsia_13-3-1600x1067.jpg",1600,1067,true],"1536x1536":["https:\/\/uwr.edu.pl\/wp-content\/uploads\/2024\/09\/Rafal-Grzelczak_fot.Alina-Metelytsia_13-3-1536x1024.jpg",1536,1024,true],"2048x2048":["https:\/\/uwr.edu.pl\/wp-content\/uploads\/2024\/09\/Rafal-Grzelczak_fot.Alina-Metelytsia_13-3-2048x1365.jpg",2048,1365,true]},"post_excerpt_stackable_v2":"

The University of Wroc\u0142aw has high esteem for finalists and laureates of Olympiads, and candidates with excellent secondary school-leaving exam results, but most of all for those who wish to develop their interests and become \u201cYoung Researchers\u201d. Meet Rafa\u0142 Grzelczak.<\/p>\n","category_list_v2":"News<\/a>, UL: Studies and Students<\/a>","author_info_v2":{"name":"sfalecki","url":"https:\/\/uwr.edu.pl\/en\/author\/sfalecki\/"},"comments_num_v2":"0 comments","acf":[],"yoast_head":"\nMolecular machine designer \u2013 Rafa\u0142 Grzelczak - Uniwersytet Wroc\u0142awski<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/uwr.edu.pl\/en\/molecular-machine-designer-rafal-grzelczak\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Molecular machine designer \u2013 Rafa\u0142 Grzelczak - Uniwersytet Wroc\u0142awski\" \/>\n<meta property=\"og:description\" content=\"The University of Wroc\u0142aw has high esteem for finalists and laureates of Olympiads, and candidates with excellent secondary school-leaving exam results, but most of all for those who wish to develop their interests and become \u201cYoung Researchers\u201d. 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