
pl. Uniwersytecki
Zainteresowania
- gaba
- receptor
- binding
- gabaa receptor
- gabaa receptors
- biophysics
- gating
- modulation
- mutagenesis
- chemical physics
Najnowsze publikacje
- The C loop at the orthosteric binding site is critically involved in GABAA receptor gating
- Mutations of α1F45 residue of GABAA receptor loop G reveal its involvement in agonist binding and channel opening/closing transitions
- The β2 subunit E155 residue as a proton sensor at the binding site on GABA type A receptors
- Interaction between GABAA receptor α1 and β2 subunits at the N-terminal peripheral regions is crucial for receptor binding and gating
- Binding site opening by loop C shift and chloride ion-pore interaction in the GABAA receptor model
- Distinct Modulation of Spontaneous and GABA-Evoked Gating by Flurazepam Shapes Cross-Talk Between Agonist-Free and Liganded GABAA Receptor Activity
- Refer analysis of a1b2g2 GABA type a receptor suggests a slight phase shift between principal and complementary subunits at the extracellular domain upon channel activation
- Molekularne mechanizmy modulacji receptora GABAA przez protony