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Biotechnologists of the University of Wrocław about galectin-7 in the Journal of Medicinal Chemistry

In one of the most prestigious journals in the world specializing in the medicinal chemistry and discovering pharmaceuticals, The Journal of Medicinal Chemistry (ACS), a publication appeared which describes the discovery of nanobodies blocking galectine-7 and of which the co-authors are dr Natalia Porębska and prof. dr hab. Łukasz Opaliński from the Department of Medical Biotechnology. The publication came into being in cooperation with the prof. Yves St Pierre team from INRS Quebec, Canada.

Galectin-7 is strongly connected to the development of an array of neoplasms. Not only its inhibitors but also its blockers are sought-after, which could lead to the inactivation of this protein and, therefore, be used as the anticancer medicine.

The wrought nanobodies specific regarding galectin-7 allow for imaging this protein in vivo and can also inhibit its oncogenic properties.

The article is available in Open Access on the website.

Source: Faculty of Biotechnology of the University of Wrocław

Added by: E.K.

Date of publication: 06.05.2025

Translated by Maja Zaucha (student of English Studies at the University of Wrocław) as part of the translation practice.

The project “Integrated Program for the Development of the University of Wrocław 2018-2022” co-financed by the European Union from the European Social Fund

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